National surveillance of CJD in the United Kingdom (UK) was initiated in May 1990 in response to a recommendation in the Southwood Committee Report of the Working Party on Bovine Spongiform Encephalopathy (BSE), to identify any changes in the pattern of CJD that might be attributable to human infection with the agent responsible for the emergence of BSE in cattle. Such a change was recognised in 1996 when ten cases with a clinical and pathological picture distinct from that usually seen in sporadic CJD were described by the Unit - a new variant of CJD.
The NCJDRSU has comprehensive mechanisms in place for the ascertainment of cases of variant and sporadic CJD in the UK. Suspect cases are classified according to internationally recognised published criteria, last updated in January 2017 and applied to all referrals from January 2017.
- Diagnostic criteria
- NCJDRSU protocol for CJD surveillance across the UK
- Glossary of medical and scientific terms
More information on the reporting system, data and reports, diagnosis and testing can be found by clicking the following links or via the menu tab 'Surveillance' above.