1989

Scott PR, Aldridge BM, Clarke M, Will RG. Bovine spongiform encephalopathy in a cow in the United Kingdom. JAVMA 1989;195; 1745-1747.

1990

Will RG. Prion Disease. Lancet 1990; 336: pp369.

Will RG. Is there a potential risk of transmission of BSE to the human population and how may this be assessed? In: Subacute Spongiform Encephalopathies - Proceedings of a Seminar in the CEC Agricultural Research Programme held in Brussels, 12-14 November 1990. Eds: R. Bradley, M. Savey & B. Marchant. Published by Kluwer Academic Publishers 1991.

1991

Bell JE and Ironside JW. Department of Health National Surveillance of Creutzfeldt-Jakob Disease. Bulletin of the Royal College of Pathologists, April 1991, pp 9-10.

Will RG. Subacute spongiform encephalopathies. In: Current Medicine 3, Ed. D.H. Lawson, Published: Churchill Livingston, Edinburgh. 1991; Chapter 9 pp 127-143.

Will RG. Comment: Slow virus infection of the central nervous system. Current Medical Literature (Neurology), 1991 Volume 7, Number 3, September 1991, pp 67-69.

Will RG. An overview of Creutzfeldt-Jakob disease associated with the use of human pituitary growth hormone. Develop. Biol. Standard 1991; Vol 75: 85-86.

Will RG. Epidemiological surveillance of Creutzfeldt-Jakob disease in the United Kingdom. Eur. J. Epidemiol. 1991; 7(5): 460-465.

Will RG. The spongiform encephalopathies. JNNP 1991; 54(9): 761-763.

1992

Bell JE, Ironside JW, McCardle L & Will RG. Creutzfeldt-Jakob disease - UK Neuropathology Project. Neuropathology and Applied Neurobiology 1992; 18: 302.

Brown P, Preece MA, Will RG. 'Friendly fire' in medicine: hormones, homografts and Creutzfeldt-Jakob disease. Lancet 1992; 340: 24-27.

Esmonde TFG, Will RG. Magnetic resonance imaging in Creutzfeldt-Jakob disease. Ann. Neurol. 1992; 31(2): 230.

Esmonde TFG, Will RG. Transmissible Spongiform Encephalopathies and their Relationship to Human Neurodegenerative Disease. British Journal of Hospital Medicine 1992; 49(6): 400-404.

Esmonde TFG, Will RG. Creutzfeldt-Jakob disease in Scotland and Northern Ireland 1980-1989. Scottish Medical Journal 1992; 37: 181-184.

Ironside JW, Bell JE, McCardle L & Will RG. Neuronal and glial reactions in Creutzfeldt-Jakob Disease. Neuropathology and Applied Neurobiology 1992; 18: 295.

Ironside JW, Bell JE, Hayward P. Glial and neuronal reactions in Creutzfeldt-Jakob disease. Clinical Neuropathology 1992; ii: pp226.

Will RG, Esmonde TFG, Matthews WB. Creutzfeldt-Jakob Disease Epidemiology. In: Prion Diseases of Humans and Animals. Eds: Prusiner SB, Collinge J, Powell J, Anderton B. 1992; ppp 188-199.

Will RG. BSE and the spongiform encephalopathies. In: Recent Advances in Clinical Neurology. Ed: Kennard C. 1992; Chapter 5, pp 115-127.

Will RG, Ironside JW, Bell JE. Bovine spongiform Encephalopathy and risk to health. BMJ 1992; 305: 53.

Will RG. Prions in animals. Virus and Life 1992; 4: 6--8.

1993

Bell JE, Ironside JW. How to tackle a possible CJD necropsy. J Clin Path 1993; 46: 193-197.

Bell JE, Ironside JW. Neuropathology of spongiform encephalopathies in humans. British Medical Bulletin 1993; 49: 738-777.

Esmonde TFG, Lueck CJ, Symon L. Duchen LW, Will RG. Creutzfeldt-Jakob Disease and Lyophilised Dura Mater Grafts: Report of Two Cases and a Review of the Literature. JNNP 1993; 56: 999-1000.

Esmonde TFG, Will RG, Slattery JM, Knight R, Harries-Jones R, de Silva R, Matthews WB. Creutzfeldt-Jakob Disease and Blood Transfusion. Lancet 1993;341: 205-207.

Ironside JW, McCardle L, Hayward P & Bell JE. Ubiquitin immunocytochemistry in human spongiform encephalopathies. Neuropathology and Applied Neurobiology 1993; 19: 134-140.

Ironside JW, Barrie C, McCardle L & Bell JE. Microglial cell reactions in human spongiform encephalopathies. Neuropathology & Applied Neurobiology 1993; 19(2): 57.

Prion Protein: Distribution and Significance in Creutzfeldt-Jakob disease - Thesis submission by Philip Hayward for Degree of Honours BSc (Medical Science) in Department of Pathology.

Sawcer SJ, Yuill GM, Esmonde TFG, Estibeiro P, Ironside JW, Bell JE, Will RG. Creutzfeldt-Jakob disease in an individual occupationally exposed to BSE. Lancet 1993; 341: 642.

The Morphology, Distribution and Cellular Reactions to Amyloid Plaques in Neurodegenerative Diseases and the Aged Brain. Thesis submission to Edinburgh University by Christopher Turner for the degree of BSc (Hons) (Med Sci) in the Department of Pathology, Session 1992-1993.

Turner C, Bell JE, Ironside JW. Localisation of microglia in CNS amyloid plaques: an immunocytochemical and confocal microscopic study. J Pathol 1993; 170: 401A.

Will RG. Abstract: Prion Diseases in Man. 8th Wye College Neuropathology Symposium, 5-9 July 1993.

Will RG. Epidemiology of Creutzfeldt-Jakob disease. British Medical Bulletin 1993; 49: 960-971.

Will RG. The surveillance of Creutzfeldt-Jakob disease in the United Kingdom. In: Transmissible Spongiform Encephalopathies. Proceedings of a Consultation on BSE with the Scientific Veterinary Committee of the European Communities held in Brussels 14-15 September 1993. Eds: Bradley R & Marchant B. pp 143.

1994

Advisory Committee on Dangerous Pathogens. Precautions for work with human and animal transmissible spongiform encephalopathies. HMSO 1994 (ISBN 0 11 321805 2).

Alperovitch A, Brown P, Weber T, Pocchiari M, Hofman A and Will R. Incidence of Creutzfeldt-Jakob disease in Europe in 1993 (Letter). Lancet 1994; 343: 918.

Brown P, Cervenakova L, Goldfarb L, McCombie WR, Rubenstein R, Will RG, Pocchiari M, Martinez-Lage JF, Scalici C, Masullo C, Graupera G, Ligan J, Gajdusek DC. Iatrogenic Creutzfeldt-Jakob disease: an example of the interplay between ancient genes and modern medicine. Neurology 1994; 44: 291-293.

Brown P, Kenney K, Little B, Ironside JW, Safar J, Rohwer R, Roos R, Wollmann R, Gibbs CJ Jr, Gajdusek DC. Comparison of clinical features, neuropathology and intracerebral distribution of PrP amyloid protein in the brains of patients with spongiform encephalopathy. Neurobiol Aging 1994; 15 (Suppl 1): S150.

de Silva R, Esmonde TFG. Iatrogenic transmission of Creutzfeldt-Jakob disease: an update. CNS Drugs 1994; 2(2): 96-101.

de Silva R, Ironside JW, Barrie C, Esmonde TFG, Bell JE, Will RG. Amyloid plaques in Creutzfeldt-Jakob disease: prevalence and clinical correlates. Ann Neurol 1994; 36(2): 273.

de Silva R, Ironside JW, McCardle L, Esmonde T, Bell J, Will R, Windl O, Dempster M, Esitbeiro P, Lathe R. Neuropathological phenotype and "prion protein" genotype correlation in sporadic Creutzfeldt-Jakob disease. Neuroscience Letters 1994; 179: 50-52.

de Silva R, Windl O, Dempster M, Estibeiro P, Esmonde TFG, Lathe R, Ironside JW, Will RG. Prion protein genotype in Creutzfeldt-Jakob disease: the Edinburgh experience. Ann Neurol 1994; 36(2): 272.

Esmonde TFG, Will RG, Ironside J, Cousens S. Creutzfeldt-Jakob disease: a case-control study. Neurology 1994; 44 (Suppl 2): A193.

Gray F, Chretien F, Cesaro P, Chatelain J, Beaudry P, Laplanche JL, Mikol J, Bell J, Gambetti P, Degos JD. Creutzfeldt-Jakob disease and cerebral amyloid angiopathy. Acta Neuropathol 1994; 88: 106-111.

Hayward PAR, Bell JE, Ironside JW. Prion protein immunocytochemistry: reliable protocols for the investigation of Creutzfeldt-Jakob disease. Neuropathology and Applied Neurobiology 1994; 20: 375-383.

Ironside JW, DeArmond SJ. Human prion diseases (Workshop 4). Brain Pathol 1994; 4: 313-315.

McNaughton H, Will RG. Creutzfeldt-Jakob disease presenting as stroke: an analysis of 30 cases. Ann Neurol 1994; 36(2):313.

Prion Protein Pathology in Sporadic Creutzfeldt-Jakob Disease. Thesis submission to Edinburgh University by Simon Thomas MacDonald for the degree of BSc (Hons) (Med Sci) in the Department of Pathology 1994.

Sutherland K, Barrie C and Ironside JW. Automatic quantification of amyloid plaque formation in human spongiform encephalopathy. Neurodegeneration 1994; 3: 293-300.

Sutherland K, Barrie C, Ironside JW. Automatic image analysis of PrP plaque formation in human spongiform encephalopathy. Neuropathology and Applied Neurobiology 1994; 20: 518.

Sutherland K, Ironside JW. Novel application of image analysis to the detection of spongiform change. Analytical and Quantitative Cytology and Histology 1994; 16(6): 430-434.

Sutherland K, Rutovitz D, Bell JE, Ironside JW. Evaluation of a novel application of image analysis to spongiform change detection. Proceedings of the IEEE International Conference in Imaging Processing, Austin TX, November 1994, pp 378-381.

Tobias E, Mann C, Bone I, de Silva R, Ironside JW. A case of Creutzfeldt-Jakob disease presenting with cortical deafness (Letter). JNNP 1994; 57(7): 872-873.

Wientjens DPWM, Will RG, Hofman A. Creutzfeldt-Jakob disease: a collaborative study in Europe. JNNP 1994; 57: 1285-1299.

Will RG and Wilesmith JW. Response to the article: "Vertical transfer of prion disease" by Lacey and Dealler. Human Reproduction 1994; 9(10): 1792-1800.

Will RG. Commentary: Gene influences of Creutzfeldt-Jakob disease. Lancet 1994; 344: 1310-1311.

Will RG. The United Kingdom and European CJD Surveillance System. Highlights and Developments. Abstract presented at OIE meeting in Paris 1-2 September 1994.

1995

Bateman D, Hilton D, Love S, Zeidler M, Beck J, Collinge J. Sporadic Creutzfeldt-Jakob disease in a 18-year old in the UK. Lancet 1995; 346:1155-1156.

Brown P, Kenney K, Little B, Ironside J, Will R, Cervenakova L, Bjork RJ, San Martin RA, Safar J, Roos R, Haltia M, Gibbs CJ Jr, Gajdusek DC. Intracerebral distribution of infectious amyloid protein in spongiform encephalopathy. Ann Neurol 1995; 38: 245-253.

Budka H, Aguzzi A, Brown P, Brucher JM, Bugiani O, Collinge J, Diringer H, Gullotta F, Halti M, Hauw JJ, Ironside JW, Kretzschmar HA, Lantos PL, Masullo C, Pocchiari M, Schlote W, Tateishi J, Will RG. Tissue Handling in Suspected Creutzfeldt-Jakob Disease (CJD) and Other Human Spongiform Encephalopathies (Prion Diseases). Brain Pathology 1995; 5:319-322.

Budka H, Aguzzi A, Brown P, Brucher JM, Bugiani O, Gullotta F, Haltia M, Hauw J-J, Ironside JW, Jellinger K, Kretzschmar HA, Lantos PL, Masullo C, Schlote W, Tateishi J, Weller RO. Neuropathological Diagnostic Criteria for Creutzfeldt-Jakob Disease (CJD) and Other Human Spongiform Encephaloapthies (Prion Diseases). Brain Pathology 1995; 5: 459-466.

Collinge J, Palmer MS, Sidle KCL, Gowland I, Medori R, Ironside J, Lantos P. Transmission of fatal familial insomnia to laboratory animals. Lancet 1995; 346: 569-570.

Delasnerie-Laupretre N, Poser S, Pocchiari M, Wientjens DPWM, Will RG. Creutzfeldt-Jakob disease in Europe. Lancet 1995; 346:898.

Goodbrand IA, Ironside JW, Nicolson D, Bell JE. Prion protein accumulation in the spinal cords of patients with sporadic and growth hormone associated Creutzfeldt-Jakob disease. Neuroscience Letters 1995; 183: 127-130.

Goodbrand IA, Nicolson D, Bell JE, Ironside JW. Prion protein localization in the spinal cord and brain stem in iatrogenic and sporadic CJD: an immunocytochemical study with pathogenetic implications. Neuropathology and Applied Neurobiology 1995; 21: 444.

Ironside JW, Bell JE. PrP immunocytochemistry in sporadic and iatrogenic CJD. Clinical Neuroscience 1995; 48(Suppl): 43.

Jeffrey M, Goodbrand IA, Goodsir CM. Pathology of the transmissible spongiform encephalopathies with special emphasis on ultrastructure. Micron 1995; 26(3): 277-298.

Nicholl D, Windl O, de Silva R, Sawcer S, Dempster M, Ironside JW, Estibeiro JP, Yuill GM, Lathe R, Will RG. Inherited Creutzfeldt-Jakob disease in a British family associated with a novel 144 base pair insertion of the prion protein gene. JNNP 1995; 58: 65-69.

Pickering-Brown SM, Mann DMA, Owen F, Ironside JW, de Silva R, Roberts DA, Balderson, Cooper PN. Allelic variations in apolipoprotein E and prion protein genotype related to plaque formation and age of onset in sporadic Creutzfeldt-Jakob disease. Neuroscience Letters 1995; 187: 127-129.

Revesz T, Daniel SE, Lees AJ, Will RG. A case of progressive subcortical gliosis associated with deposition of abnormal prion protein (PrP). JNNP 1995; 58: 759-760.

Smith PEM, Zeidler M, Ironside JW, Estibeiro P, Moss TH. Creutzfeldt-Jakob disease in a dairy farmer. Lancet 1995; 346:898.

Surveillance of Creutzfeldt-Jakob Disease. Thesis submission by Dr T.F.G. Esmonde to Trinity College, University of Dublin, June 1995. Degree of MD awarded.

Sutherland K, Macdonald ST, Barrie C, Ironside JW. Assessment of neuropathological targeting in Creutzfeldt-Jakob disease: a quantitative immunocytochemical study. Neuropathology and Applied Neurobiology 1995; 15.

Will RG. Creutzfeldt-Jakob disease. Postgraduate Doctor Middle East 1995; 18: 177-182.

Will RG. Possible Creutzfeldt-Jakob disease in an adolescent. World Health Organisation Weekly Epidemiological Record 1995; 15: 105-106.

Will RG. Commentary: Scrapie revisited. BMJ 1995; 311:1075-1076.

Will RG. Creutzfeldt-Jakob disease. Postgraduate Doctor Caribbean 1995; 11: 50-56.

1996

An investigation into the use of PrP immunostaining in a dedicated laboratory for human spongiform encephalopathies. Thesis submission from Mrs L. McCardle for Fellowship of the Institute of Biomedical Scientists, London. Awarded May 1996.

Baker HF, Ridley RM, Wells GA, Ironside JW. Spontaneous spongiform encephalopathy in a monkey. Lancet 1996; 348: 955-956.

Campbell TA, Palmer MS, Will RG, Gibb WRG, Luthert PJ, Collinge J. A prion disease with a novel 96-base pair insertional mutation in the prion protein gene. Neurology 1996; 46:761-766.

Collinge J, Beck J, Campbell T, Estibeiro K, Will RG. Prion protein gene analysis in new variant cases of Creutzfeldt-Jakob disease. Lancet 1996; 348:56.

Collinge J, Sidle KCL, Meads J, Ironside J, Hill AF. Molecular analysis of prion strain variation and the aetiology of ‘new variant’ CJD. Nature 1996; 383: 685-690.

Holmes SJ, Ironside JW, Shalet SM. Neurosurgery in a patient with Creutzfeldt-Jakob disease after pituitary derived growth hormone therapy in childhood. JNNP 1996; 60(3): 333-335.

Ironside JW. Neuropathological diagnosis of human prion disease: morphological studies. In: Baker H, Ridley RM, eds. Methods in Molecular Medicine: Prion Diseases. Totowa, NJ: Humana Press Inc, 1996:35-57.

Ironside JW, Bell JE. The ‘high-risk’ neuropathological autopsy in AIDS and Creutzfeldt-Jakob disease: principles and practice. Neuropathology and Applied Neurobiology 1996; 22: 388-393.

Ironside JW. Prion diseases: epidemiology and pathology. Neuropathology and Applied Neurobiology 1996; 22: 173-175.

Ironside JW, Sutherland K, Bell JE, McCardle L, Barrie C, Estibeiro K, Zeidler M, Will RG. A new variant of Creutzfeldt-Jakob disease: neuropathological and clinical features. Cold Spring Harbour Symposia on Quantitative Biology 1996; LXI: 523-530.

Ironside JW. Prion diseases: update on Creutzfeldt-Jakob disease. Neuropathology and Applied Neurobiology 1996; 22: 446.

Ironside JW, Goodbrand IA, Bell JE, Will RG. PrP accumulation in sporadic and iatrogenic CJD. Neuropathology and Applied Neurobiology 1996; 22: 7.

Ironside JW. Human prion diseases. J Neural Transm 1996; 47 (Suppl): 231-246.

Ironside JW. Review: Creutzfeldt-Jakob disease. Brain Pathol 1996; 6: 379-388.

Kretzschmar HA, Ironside JW, DeArmond SJ, Tateishi J. Diagnostic criteria for sporadic Creutzfeldt-Jakob disease. Arch Neurol 1996; 53: 913-920.

Lasmézas GI, Deslys J-P, Demaimay R, Adjou KT, Lamoury F, Dormont D, Robain O, Ironside J, Hauw J-J. BSE transmission to macaques. Nature 1996; 381: 743-744.

MacDonald ST, Sutherland K, Ironside JW. A quantitative and qualitative analysis of prion protein immunohistochemical staining in Creutzfeldt-Jakob disease using four anti prion protein antibodies. Neurodegeneration 1996; 5: 87-94.

MacDonald ST, Sutherland K, Ironside JW. Prion protein genotype and pathological phenotype studies in sporadic Creutzfeldt-Jakob disease. Neuropathology and Applied Neurobiology 1996; 22: 285-292.

Peet R, Sutherland K, Ironside JW. Quantitative methods in the analysis of a new variant of Creutzfeldt-Jakob disease. Electronic Journal of Pathology and Histology 1996; 2: 964-967.

Roos RAC, Wintzen AR, Will RG, Ironside JW, van Duinen SG. Een patient met de ziekte van Creutzfeldt-Jakob na behandeling met humaan groeihormoon. Ned Tijdschr Geneeskd 1996; 40(22):1190-1193.

Sutherland K, Goodbrand IA, Bell JE, Ironside JW. Objective quantification of prion protein in spinal cords of cases of Creutzfeldt-Jakob disease. Analytical Cellular Pathology 1996; 10: 25-35.

Sutherland K, Ironside JW. Quantifying spongiform change in the brain by image analysis. Microscopy & Analysis, January1996: 15-16.

Sutherland K, Macdonald S, Ironside JW. Quantification and analysis of the neuropathological features of Creutzfeldt-Jakob disease. Journal of Neuroscience Methods 1996; 64: 123-132.

Sutherland K, Ironside JW. Automatic quantification of astrocyte numbers in Creutzfeldt-Jakob disease. Neuropathology and Applied Neurobiology 1996; 22: 7.

Sutherland K, Ironside JW. Automatic computerised image anlaysis of neuro-pathology in Creutzfeldt-Jakob disease. In: Transmissible Subacute Spongiform Encephalopathies: Prion Diseases, Eds: Court L., Dodet B., Elsevier, Paris 1996: 89-95.

Wientjens DPWM, Davanipour Z, Hofman A, Kondo K, Matthews WB, Will RG, van Duijn CM. Risk factors for Creutzfeldt-Jakob disease: a re-analysis of case-control studies. Neurology 1996; 46:1287-1291.

Wientjens,D.P.W.M., Delasnerie-Laupretre,N., Hofman,A., Poser,S., Pocchiari,M. and Will,R.G. Incidence of Creutzfeldt-Jakob disease in Europe. Neurology 1996; 46: A290.

Will RG, Ironside JW, Hornlimann B, Zeidler M. Creutzfeldt-Jakob disease (Letter). Lancet 1996; 347:65-66.

Will RG, Ironside JW, Zeidler M, Cousens SN, Estibeiro K, Alperovitch A, Poser S, Pocchiari M, Hofman A, Smith PG. A new variant of Creutzfeldt-Jakob disease in the UK. Lancet 1996; 347:921-925.

Will RG, Zeidler M, Brown P, Harrington MG, Lee KH, Kenney KL. Cerebrospinal fluid test for new variant Creutzfeldt-Jakob disease. Lancet 1996; 348:955-956.

Will RG, Zeidler M. Diagnosing Creutzfeldt-Jakob disease. BMJ 1996; 313:833-834.

Will RG. Incidence of Creutzfeldt-Jakob disease in the European Community. In: Gibbs C.J. Jr, ed. Bovine Spongiform Encephalopathy: The BSE Dilemma, Springer-Verlag New York Inc, 1996; Chapter 27, pp 364-374.

Will RG. Surveillance of Prion Diseases in Humans. In: Baker H, Ridley RM, eds. Methods in Molecular Medicine: Prion Diseases. Totowa, NJ: Humana Press Inc, 1996:119-137.

Will RG. Surveillance of Creutzfeldt-Jakob disease. Science in Parliament 1996; 53(6): 4-5.

Will RG. Are prions relevant to transfusion? Transfusion Medicine 1996; 6(Suppl 2): 1.

Windl O, Dempster M, Estibeiro JP, Lathe R, de Silva R, Esmonde T, Will R, Springbett A, Campbell TA, Sidle KCL, Palmer MS, Collinge J. Genetic basis of Creutzfeldt-Jakob disease in the United Kingdom: a systematic analysis of predisposing mutations and allelic variation in the PRNP gene. Hum Genet 1996; 98: 259-264.

Young GR, Fletcher NA, Zeidler M, Estibeiro KL, Ironside JW. Creutzfeldt-Jakob disease in a beef farmer. Lancet 1996; 348:610-611.

Zeidler M, Will RG, Ironside JW, Sellar R, Wardlaw J. Creutzfeldt-Jakob disease and bovine spongiform encephalopathy. Magnetic resonance imaging is not a sensitive test for CJD (Letter). BMJ 1996; 312: 844.

1997

Bell JE, Ironside JW. Principles and practice of "high-risk" brain banking. Neuropathology and Applied Neurobiology 1997; 23: 281-288.

Bell JE, Gentleman SM, Ironside JW, McCardle L, Lantos PL, Doey L, Lowe J, Fergusson J, Luthert P, McQuaid S. Prion protein immunocytochemistry - UK five centre consensus report. Neuropathology and Applied Neurobiology 1997; 23: 26-35.

Bruce ME, Will RG, Ironside JW, McConnell I, Drummond D, Suttie A, McCardle L, Chree A, Hope J, Birkett C, Cousens S, Freaser H, Bostock CJ. Transmissions to mice indicate that "new variant" CJD is caused by the BSE agent. Nature 1997; 389: 498-501.

Cousens,SN, Vynnycky E, Zeidler M, Will RG and Smith PG. Predicting the CJD epidemic in humans. Nature 1997; 385:197-198.

Cousens SN, Zeidler M, Esmonde TF, De Silva R, Wilesmith JW, Smith PG, Will RG. Sporadic Creutzfeldt-Jakob disease in the United Kingdom: analysis of epidemiological surveillance data for 1970-96. BMJ 1997; 315: 389-395.

De Silva R, Findlay C, Awad I, Harries-Jones R, Knight R, Will R. Creutzfeldt-Jakob disease in the elderly. Postgrad Med J 1997; 73: 557-559.

Diringer H, Beekes M, Ozel M, Simon D, Queck I, Cardone F, Pocchiari M, Ironside JW. Highly infectious purified preparations of disease-specific amyloid of transmissible spongiform encephalopathies are not devoid of nucleic acids of viral size. Intervirology 1997; 40: 238-46.

Hill AF, Zeidler M, Ironside J, Collinge J. Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy. Lancet 1997; 349: 99-100.

Hill AF, Will RG, Ironside J, Collinge J. Type of prion protein in UK farmers with Creutzfeldt-Jakob disease. Lancet 1997; 350: 188.

Ironside JW , Bell JE. Pathology of Prion Diseases. In: Collinge J , Palmer MS. (Eds.) Prion Diseases, 1997 pp. 25-50. Oxford:Oxford University Press.

Ironside JW. Transmissible Spongiform Encephalopathies. In: Greenwood D, Slack RCB, Peutherer JF. (Eds.) Medical Microbiology, 1997 15th edn. pp. 548-555. Edinburgh:Churchill Livingstone.

Ironside JW. New variant Creutzfeldt-Jakob disease in the UK: clinical and pathological studies. Brain Pathology 1997; 7: 1243-1245.

Ironside JW. Transmissible spongiform encephalopathies: the relationship between Creutzfeldt-Jakob disease and bovine spongiform encephalopathy. Current Opinion in Infectious Diseases 1997; 10: 1-14.

Ironside JW, Bell JE. Florid plaques and new variant Creutzfeldt-Jakob disease. Lancet 1997; 350: 1475.

Ironside JW. New variant CJD. In: Recent Advances in Histopathology. Eds: Lowe D, Underwood JCE, Churchill Livingstone, Edinburgh 1997: 944.

Ironside JW. General features of prion diseases. In: Clinical and Pathological Basis of Neurodegeneration. Eds: Trojanowski JQ, Williams and Wilkins, Baltimore 1997: 943.

Ironside JW. The new variant form of Creutzfeldt-Jakob disease: a novel prion protein amyloid disorder. Amyloid 1997; 4: 66-69.

McCardle L. Human prion diseases (Biomedical Comment). British Journal of Biomedical Science. 1997; 54: 2-4.

McLean CA, Ironside JW, Masters CL. Comparative neuropathology in kuru and new variant CJD. Brain Pathology 1997; 7: 1247-1248.

McNaughton HK, Will RG. Creutzfeldt-Jakob disease presenting acutely as stroke: an analysis of 30 cases. Neurological Infections and Epidemiology 1997; 2: 19-24.

Nicoll JA, Burnett C, Love S, Graham DI, Dewar D, Ironside JW, Stewart J, Vinters HV. High frequency of apolipoprotein E epsilon 2 allele in haemorrhage due to cerebral amyloid angiopathy. Annals of Neurology 1997; 41: 716-721.

Raymond GJ, Hope J, Kocisko DA, Priola SA, Raymond LD, Bossers A, Ironside JW, Will RG, Chen SG, Petersen RB, Gambetti P, Smits A, Rubenstein R, Lansbury Jr PT, Caughey B. Molecular assessment of the potential transmissibilities of BSE and scrapie to humans. Nature 1997; 388: 228-229.

Sellar RJ, Will RG, Zeidler M. MR imaging of new variant Creutzfeldt-Jakob disease: the pulvinar sign. Neuroradiology 1997; 39: S53.

Stewart B, Ironside JW, Fraser JR. Quantification of scrapie pathology following infection by the intramuscular, intraperitoneal and oral routes. Brain Pathology 1997; 7: 1380.

Sutherland K, De Silva R, Will RG. Clinical diagnosis of Creutzfeldt-Jakob disease using a multi-layer perceptron neural network classifier. Journal of Intelligent Systems 1997; 7(1-2): 1-18.

Whittle IR, Will RG, Ironside JW. Brain biopsy and patients with atypical presentations of sporadic Creutzfeldt-Jakob disease. JNNP 1997; 63: 547-558.

Will RG, Knight RSG, Zeidler M, Stewart G, Ironside JW, Cousens SN, Smith PG. Reporting of suspect new variant Creutzfeldt-Jakob disease. Lancet 1997; 349: 847.

Will RG. A new variant of Creutzfeldt-Jakob Disease in the UK. Society for Veterinary Epidemiology and Preventative Medicine - Proceedings. 1997; 1-278.

Will RG. New variant Creutzfeldt-Jakob disease. Alzheimer's Review 1997; 7(1): 145-147.

Zeidler M, Johnstone EC, Bamber RWK, Dickens CM, Fisher CJ, Francis AF, Goldbeck R, Higgo R, Johnson-Sabine EC, Lodge GJ, McGarry P, Mitchell S, Tarlo L, Turner M, Ryley P, Will RG. New variant Creutzfeldt-Jakob disease: psychiatric features. Lancet 1997; 350: 908-910.

Zeidler M, Stewart GE, Barraclough CR, Bateman DE, Bates D, Burn DJ, Colchester AC, Durward W, Fletcher NA, Hawkins SA, Mackenzie JM, Will RG. New variant Creutzfeldt-Jakob disease: neurological features and diagnostic tests. Lancet 1997; 350: 903-907.

Zeidler M, Stewart G, Cousens SN, Estibeiro K, Will RG. Codon129 genotype and new variant CJD. Lancet 1997; 350: 668.

Zeidler M, Estibeiro K, Will RG. The genetics of Creutzfeldt-Jakob disease in the United Kingdom. JNNP 1997; 206.

1998

Baker HF, Ridley RM, Wells GAH, Ironside JW. Prion protein immunohistochemical staining in the brains of monkeys with transmissible spongiform encephalopathy. Neuropathology and Applied Neurobiology 1998; 24: 476-486.

Chamberland ME, Epstein J, Dodd RY, Persing D, Will RG, DeMaria Jr A, Emmanuel JC, Pierce B, Khabbaz R. Blood safety. Emerging Infectious Dieases 1998; 4(3): 410-411.

Collie DA, Sellar RJ, Ironside J, Zeidler M, Stewart G, Knight R, Will RG. New variant Creutzfeldt-Jakob disease: diagnostic features on MRI with histopathological correlation. Proceedings of ASNR, AJNR (Suppl) 1998; 20: 139 (abstract).

Dorandeu A, Wingertsmann L, Ironside JW, Delisle M-B, Vital C, Parchi P, Montagna P, Lugaresi E, Budka, H, Gambetti P, Gray F. Neuronal apoptosis in fatal familial insomnia. Brain Pathology 1998; 8: 531-537.

Hilton DA, Fathers E, Edwards P, Ironside JW, Zajicek J. Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease. Lancet 1998; 352: 703-704.

Ironside JW. Neuropathological findings in new variant CJD and experimental transmission of BSE. FEMS Immunology and Medical Microbiology 1998; 21: 91-95.

Ironside JW. The work of the National CJD Surveillance Unit. ACP News 1998; 27-29.

Ironside JW. Creutzfeldt-Jakob disease - The Story so Far. Proceedings of the Royal College of Physicians, Edinburgh 1998; 28: 143-149.

Ironside JW, Knight RS, Will RG, Brown PW. New variant Creutzfeldt-Jakob disease is more common in Britain than elsewhere. BMJ 1998; 317: 352.

Ironside JW. New-variant Creutzfeldt-Jakob disease. Neuropathology 1998; 18(2): 131-138.

Ironside JW. Prion diseases in man. J Pathol 1998 186(3): 227-234.

Knight R, Stewart G. The new variant form of Creutzfeldt-Jakob disease. FEMS Immunology & Medical Microbiology 1998; 21: 97-100.

Knight R. Creutzfeldt-Jakob disease: clinical features, epideimology and tests. Electrophoresis 1998; 19: 1306-1310.

Knight RSG. The diagnosis of prion diseases. Parasitology 1998; 117: S3-S11.

Lee CA, Ironside JW, Bell JE, Giangrande P, Ludlam C, Esiri MM, McLaughlin JE. Retrospective neuropathological review of prion disease in UK haemophilic patients. Thromb Haemost 1998; 80(6): 909-11.

McLean CA, Ironside JW, Alpers MP, Brown PW, Cervenakova L, Anderson RMcD, Masters CL. Comparative neuropathology of kuru with the new variant of Creutzfeldt-Jakob disease: evidence for strain of agent predominating over genotype host. Brain Pathology 1998; 8: 429-437.

Nailon WH, Ironside JW. Image processing in neuropathology. In: Proceedings of the Second Workshop on Advances in Brain Morphometry, Leeds Castle, Kent, 24-26th October 1998.

Piccardo P, Dlouhy SR, Lievens PMJ, Young K, Bird DPTD, Nochlin D, Dickson DW, Vinters HV, Zimmerman TR, Mackenzie IRA, Kish SJ, Ang L-C, de Carli C, Pocchiari M, Brown P, Gibbs Jr. CJ, Gajdusek DC, Bugiani O, Ironside J, Tagliavini F, Ghetti B. Phenotypic variability of Gerstmann-Straussler-Scheinker disease is associated with prion protein heterogeneity. J Neuropathol Exp Neurol 1998; 57(10): 979-988.

Schultz DW, Lennox GG, Ironside JW, Warlow CP. Behavioural disturbance and visual hallucinations in a 78 year old man. JNNP 1998; 65(6): 933-8.

Stewart GE, Ironside JW. New variant Creutzfeldt-Jakob disease. Current Opinion in Neurology 1998; 11: 259-262.

van Duijn CM, Delasnerie-Laupretre N, Masullo C, Zerr I, De Silva R, Wientjens DPWM, Brandel J-P, Weber T, Bonavita V, Zeidler M, Alperovitch A, Poser S, Granieri E, Hofman A, Will RG. Case-control study of risk factors of Creutzfeldt-Jakob disease in Europe during 1993-95. Lancet 1998; 351: 1081-1085.

Will RG, Campbell MJ, Moss TH, Bell JE, Ironside JW. FFI cases from the United Kingdom. Brain Pathology 1998; 8: 563.

Will R. New variant Creutzfeldt-Jakob disease. In: Morrison D. ed. Prions and Brain Diseases in Animals and Humans. New York: Plenum Press, 1998:141-145.

Will RG. New Variant Creutzfeldt-Jakob Disease. The Darlington Postgraduate Journal 1998; 17(1): 35-42.

Will RG. Transmissible spongiform encephalopathy: BSE/CJD - the new variant CJD. In: Goebel K, ed. The Science and Culture Series: Nuclear Strategy and Peace Technology. International Seminar on nuclear war and planetary emergencies. Singapore: World Scientific Publishing Co. Pte. Ltd, 1998: 133-134.

Will RG. Update on surveillance of Creutzfeldt-Jakob disease in Europe. In: Office International des Epizooties , ed. Epidemiological studies and research on transmissible spongiform encephalopathies. Paris: Office International des Epizooties, 1998: 10-12.

Will RG. New variant Creutzfeldt-Jakob disease. In: Brown F, Griffiths E, Horaud F, Petricciani JC, eds. Safety of Biological Products prepared from Mammalian Cell Culture. Basel: Karger. 1998: 79-84.

Will RG, Alperovitch A, Poser S, Pocchiari M, Hofman A, Mitrova E, De Silva R, D'Alessandro M, Delasnerie-Laupretre N, Zerr I, van Duijn C. Descriptive epidemiology of Creutzfeldt-Jakob disease in six European countries, 1993-1995. Ann Neurol 1998; 43: 763-767.

Will RG, Kimberlin RH. Creutzfeldt-Jakob disease and the risk from blood or blood products. Vox Sang 1998; 75: 178-180.

Will RG. Epidemiology and Creutzfeldt-Jakob disease. In: Sterilization of Medical Products. Eds: R.F. Morrissey, JB Kowalski. Polyscience Publications Inc., Champlain, N.Y. pp 202-211.

Zeidler M, Will RG, Ironside JW, Sellar R, Wardlaw J. Creutzfeldt-Jakob disease and bovine spongiform encephalopathy. Magnetic resonance imaging is not a sensitive test for Creutzfeldt-Jakob disease. British Medical Journal 1998; 312: 844.

1999

Alperovitch A, Zerr I, Pocchiari M, Mitrova E, de Pedro Cuesta J, Hegyi I, Collins S, Kretzschmar H, van Duijn C, Will RG. Codon 129 prion protein genotype and sporadic Creutzfeldt-Jakob disease. Lancet 1999; 353: 1673-1674 .

Bruce ME, Will RG, Ironside JW, Fraser H. Comparison of the biological characteristics of BSE and CJD in mice. In: Alzheimer's Disease and Related Disorders Eds: Iqbal K, Swaab DF, Winblad B, Wisniewski HM. John Wiley, London, 1999: 553-560.

Churchill D, Churchill DJ, Will RG. Organophosphate exposure and variant Creutzfeldt-Jakob disease. Lancet 1999; 353: 1410.

Cousens SN, Linsell L, Smith PG, Chandrakumar M, Wilesmith JW, Knight RSG, Zeidler M, Stewart G, Will RG. Geographical distribution of variant CJD in the UK (excluding Northern Ireland). Lancet 1999; 353: 18-21.

Gray F, Chretien F, Adle-Biassette H, Dorandeu A, Ereau T, Delisle M-B, Kopp N, Ironside JW, Vital C. Neuronal apoptosis in Creutzfeldt-Jakob disease. Journal of Neuropathology and Experimental Neurology 1999; 58: 321-328.

Greene JD, Hidges JR, Ironside JW, Warlow CP. Progressive aphasia with rapidly progressive dementia in a 49 year old woman. JNNP 1999; 66: 238-243.

Hill AF, Butterworth RJ, Joiner S, Jackson G, Rossor MN, Thomas DJ, Frosh A, Tolley N, Bell JE, Spencer M, King A, Al-Sarraj S, Ironside JW, Lantos PL, Collinge J. Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples. Lancet 1999; 353: 183-189.

Ironside JW. New variant Creutzfeldt-Jakob disease. In: Recent Advances in Histopathology eds: Lowe DG, Underwood JCE. Churchill Livingstone, Edinburgh. 1999: 1-22.

Ironside JW. nvCJD: exploring the limits of our understanding. Biologist 1999; 46: 172-176.

Knight R. The relationship between new variant Creutzfeldt-Jakob disease and bovine spongiform encephalopathy. Vox Sanguinis 1999; 76: 203-208.

Macleod MA, Knight RSG. New variant Creutzfeldt-Jakob disease. Cattle Practice 1999; 7(2): 211-214.

Macleod MA, Knight R, Stewart G, Zeidler M, Will R. Clinical features of nvCJD. European Journal of Neurology 1999; 6(3): 26-27 (abstract).

Mallucci GR, Campbell TA, Dickinson A, Beck J, Holt M, Plant G et al. Inherited prion diseases with alanine to valine mutation at codon 117 in the prion protein gene. Brain 1999; 122: 1823-1837.

Manson JC, Jamieson E, Baybutt H, Tuzi NL, Barron R, McConnell I et al. A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform ecnecphalopathy. The EMBO Journal 1999; 18: 6855-6864.

Nailon WH, Ironside JW. Creutzfeldt-Jakob disease - statistical texture analysis of abnormal prion protein. In: Proceedings of the first joint meeting of the Biomedical Eningeering Society (BMES) and the 21st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS), Atlanta, Georgia, 13-16 October 1999.

Nailon WH, Ironside JW. Quantitative image analysis of thalamic pathology in new variant Creutzfeldt-Jakob disease. In: Proceedings of Medical Image Understanding and Analysis (MIUA'99), Examinations School, Oxford, 19-20th July 1999.

Richard M, Biacabe AG, Perret-Liaudet A, McCardle L, Ironside JW, Kopp N. Protection of personnel and environment against Creutzfeldt-Jakob disease in pathology laboratories. Clinical Experimental Pathology 1999; 47: 192-200.

Scott MR, Will RG, Ironside J, Nguyen H-OB, Tremblay P, DeArmond SJ, Prusiner SB. Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans. PNAS 1999; 96(26): 15137-15142.

Shimizu S, Hoshi K, Muramoto T, Homma M, Ironside JW, Kuzuhara S, Sato T, Yamamoto T, Kitamoto T. Creutzfeldt-Jakob disease with florid-type plaques after cadaveric dura mater grafting. Arch Neurol 1999; 36: 357-362.

Turner ML, Ironside JW. New variant Creutzfeldt-Jakob disease: the risk of transmission by blood transfusion. Blood Reviews 1999; 12: 255-268.

Will RG, Alpers MP, Dormont D, Schonberger LB, Tateishi J. Infectious and sporadic prion diseases. In: Prion Biology and Diseases. Ed: Prusiner SB. Cold Spring Harbour Laboratory Press, New York. 1999; pp 465-507.

Will RG, Cousens SN, Farrington CP, Smith PG, Knight RSG, Ironside JW. Deaths from variant Creutzfeldt-Jakob disease. Lancet 1999; 353: 979.

Will RG, Ironside JW. Commentary: Oral infection by the bovine spongiform encephalopathy prion. PNAS 1999; 96: 4738-4739.

Will RG, Stewart G, Zeidler M, Macleod MA, Knight RSG. Psychiatric features of new variant Creutzfeldt-Jakob disease. Psychiatric Bulletin 1999; 23: 264-267.

Will RG. Classical CJD is not forgotten. CJD Support Network Newsletter 1999; 6-7.

Will RG. New variant Creutzfeldt-Jakob disease. Biomed & Pharmacother 1999; 53: 9-13.

Will RG. Prion related disorders. J Royal College Physicians London 1999; 33: 311-315.

Will RG. The relationship between BSE and Creutzfeldt-Jakob disease. In: International Seminar on Nuclear War and Planetary Emergencies 23rd Session. Ed: Goebel K. World Scientific Publishing Co. Pte. Ltd., Singapore. 1999; pp 38-39.

Will RG. CJD and blood transfusion. CJD Support Network Newsletter 1999; 8-9.

Will RG. The transmission of prions to humans. Acta Paediatr Suppl 1999; 433: 28-32.

Zeidler M, Knight R, Stewart G, Ironside JW, Will RG, Green AJE, Pocchiari M. Diagnosis of Creutzfeldt-Jakob disease. Routine tonsil biopsy for diagnosis of new variant Creutzfeldt-Jakob disease is not justified. BMJ 1999; 318: 538-538.

2000

Andrews NJ, Farrington CP, Cousens SN, Smith PG, Ward H, Knight RSG, Ironside JW, Will RG. Incidence of variant Creutzfeldt-Jakob disease in the UK. Lancet 2000; 356:481-482.

Green AJE, Thompson EJ, Zeidler M, Stewart G, Mackenzie J, Macleod MA, Knight RSG, Will RG. Raised concentrations of brain specific proteins in patients with sporadic and variant CJD. JNNP 2000; 69:419.

Ironside JW, Head MW, Bell JE, McCardle L, Will RG. Laboratory diagnosis of variant Creutzfeldt-Jakob disease. Histopathology 2000; 37:1-9.

Knight R, Will RG. Prion-related diseases and the central nervous system. In: Crockard A, Hayward R, Hoff JT, editors. Neurosurgery: The Scientific Basis of Clinical Practice Volume 2. Oxford: Blackwell Science, 2000: 807-814.

Knight R. Therapeutic possibilities in CJD: patents 1996-1999. Exp Opin Ther Patents 2000; 10:49-57.

Lueck CJ, McIlwaine GG, Zeidler M. Creutzfeldt-Jakob disease and the eye. I. Background and patient management. Eye 2000; 14:263-290.

Lueck CJ, McIlwaine GG, Zeidler M. Creuzfeldt-Jakob disease and the eye. II. Ophthalmic and neuro-ophthalmic features. Eye 2000; 14:291-301.

Macleod MA, Knight R, Stewart G, Zeidler M, Will R. Sensory features of variant Creutzfeldt-Jakob disease. JNNP 2000; 69:413-414.

Majeed A, Lehmann P, Kirby L, Knight R, Coleman M. Extent of misclassification of death from Creutzfeldt-Jakob disease in England 1979-96: retrospective examination of clinical records. BMJ 2000; 320:145-147.

Soto C, Kascsak RJ, Saborio GP, Aucouturier P, Wisniewski T, Prelli F, Kascsak R, Mendez E, Harris DA, Ironside J, Tagliavini F, Carp RI, Frangione B. Reversion of prion protein conformational changes by synthetic B-sheet breaker peptides. Lancet 2000; 355:192-197.

Verity CM, Nicoll A, Will RG, Devereux G, Stellitano L. Variant Creutzfeldt-Jakob disease in UK children: a national surveillance study. Lancet 2000; 356:1224-1227.

Will RG, Zeidler M, Stewart GE, Macleod MA, Ironside JW, Cousens SN, Mackenzie J, Estibeiro K, Green AJE, Knight RSG. Diagnosis of new variant Creutzfeldt-Jakob disease. Ann Neurol 2000; 47:575-582.

Zeidler M, Green AJE, Zerr I. Case 28-1999: Creutzfeldt-Jakob disease. New Engl J Med 2000;292.

Zeidler M, Ironside JW. The new variant of Creutzfeldt-Jakob disease. Rev Sci Tech Off Int Epiz 2000; 19:98-120.

Zeidler M, Sellar RJ, Collie DA, Knight R, Stewart G, Macleod MA, Ironside JW, Cousens S, Colchester AFC, Hadley DM, Will RG. The pulvinar sign on magnetic resonance imaging in variant Creutzfeldt-Jakob disease. Lancet 2000; 355:1412-1418.

Zeidler M. 14-3-3 cerebrospinal fluid protein and Creutzfeldt-Jakob disease. Ann Neurol 2000; 47:683.

Zerr I, Brandel J-P, Masullo C, Wientjens D, De Silva R, Zeidler M, Granieri E, Sampaolo S, van Duijn C, Delasnerie-Laupretre N, Will R, Poser S. European surveillance on Creutzfeldt-Jakob disease: a case-control study for medical risk factors. J Clin Epid 2000; 53:747-754.

2001

	Al-Shani R, Will RG, Warlow CP. Amount of research interest in rare and common neurological conditions: bibliometric study. BMJ 2001; 323:1461-1462.
	Barron RM, Thomson V, Jamieson E, Melton DW, Ironside JW, Will RG, Manson JC. Changing a single amino acid in the N-terminus of murine PrP alters TSE incubation time across three species barriers. The EMBO Journal 2001; 20:5070-5078.
	Brown P, Will RG, Bradley R, Asher DM, Detwiler L. Bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease: background, evolution, and current concerns. Emerging Infectious Diseases 2001; 7(1):6-16.
	Bruce ME, McConnell I, Will RG, Ironside JW. Detection of variant Creutzfeldt-Jakob disease infectivity in extraneural tissues. Lancet 2001; 358:208-209.
	Collie DA, Sellar RJ, Zeidler M, Colchester AFC, Knight R, Will RG. MRI of Creutzfeldt-Jakob disease: imaging features and recommended MRI protocol. Clinical Radiology 2001; 56:726-739.
	Cousens S, Smith PG, Ward H, Everington D, Knight RSG, Zeidler M, Stewart G, Smith-Bathgate EAB, Macleod MA, Mackenzie J, Will RG. Geographical distribution of variant Creutzfeldt-Jakob disease in Great Britain, 1994-2000. Lancet 2001; 357:1002-1007.
	Garofalo O, McFarlane EH, Iyegbe C, Whatley SA, Campbell IC, Kopp N, Will RG. Variant Creutzfeldt-Jakob disease is not associated with individual abilities to metabolise organophosphates. JNNP 2001; 71:556-567.
	Gill DS, Tredwin CJ, Gill SK, Ironside JW. The transmissible spongiform encephalopathies (prion diseases): a revie for dental surgeons. Int Dent J 2001; 51(6): 439-446.
	Green AJE, Thompson EJ, Stewart GE, Zeidler M, McKenzie JM, MacLeod M-A, Ironside JW, Will RG, Knight RSG. Use of 14-3-3 and other brain-specific proteins in CSF in the diagnosis of variant Creutzfelt-Jakob disease. JNNP 2001; 70:744-748.
	Green AJE, Knight RSG, Macleod MA, Lowman A, Will RG. Misleading results with the 14-3-3 assay for the diagnosis of Creutzfeldt-Jakob disease. Neurology 2001; 56:986.
	Head MW, Farquhar CF, Mabbott NA, Fraser JR. The transmissible spongiform encephalopathies: pathological mechanisms and strategies for therapeutic intervention. Expert Opinion Therapeutic Targets 2001; 5:569-585.
	Head MW, Tissingh G, Uitdehaag BMJ, Barkhof F, Bunn TJR, Ironside JW, Kamphorst W, Scheltens P. Sporadic Creutzfeldt-Jakob disease in a young Dutch valine homozygote: atypical molecular phenotype. Ann Neurol 2001; 50:258-261.
	Head MW. Molecular aspects of variant Creutzfeldt-Jakob disease. Dementia 2001; 1:2-7.
	Hillier CEM, Llewelyn JG, Neal JW, Ironside JW. Creutzfeldt-Jakob disease in a young person with valine homozygocity at codon 129: sporadic or variant? Journal of Neurology, Neurosurgery and Psychiatry 2001; 70:132-141.
	Ironside JW, Seilhean D, Head MW, Hauw J-J. Investigation of prion diseases. Current Topics in Pathology 2001; 95:179-205.
	Ironside JW. From BSE to Creutzfeldt-Jakob (in French). Biofutur 2001; April 2001:6-11.
	Jamieson E, Jeffrey M, Ironside JW, Fraser JR. Activation of Fas and caspase 3 prercedes PrP accumulation in 87V scrapie. Neurochemistry 2001; 12:3567-3572.
	Jamieson E, Jeffrey M, Ironside JW, Fraser JR. Apoptosis and dendritic dysfunction precede prion protein accumulation in 87V scrapie. Clinical Neuroscience and Neuropathology 2001; 12:2147-2153.
	Kapur N, Ironside J, Abbott P, Warner G, Turner A. A neuropsychological-neuropathological case study of variant Creutzfeldt-Jakob disease. Neurocase 2001; 7:261-267.
	Knight R, Collins S. Human prion diseases: cause, clinical and diagnostic aspects. In: Rabenau HF, Cinatl J, Doerr HW, editors. Prions. A challenge for science, medicine and public health system. Basel: Karger, 2001: 68-92.
	Knight R. Creutzfeldt-Jakob disease: a protein disease. Proteomics 2001; 1:763-766.
	Lasmezas CI, Fournier J-G, Nouvel V, Boe H, Marce D, Lamoury F., Kopp N, Hauw J-J., Ironside JW, Bruce M, Dormont D. Adaption of the spongiform encephalopathy agent to primates and comparison with Creutzfeldt-Jakob disease: implications for human health. Proc Natl Acad Sci USA 2001; 98(7):4142-4147.
	Lorains JW, Henry C, Agbamu DA, Rossi M, Bishop M, Will RG, Ironside JW. Variant Creutzfelt-Jakob disease in an elderly patient. Lancet 2001; 357:1339-1340.
	Lowman A, Knight R, Ironside J. Variant Creutzfeldt-Jakob disease. Practical Neurology 2001; 1:2-13.
	McLennan NF, Rennison K, Bell JE, Ironside JW. In situ hybridisation analysis of PrP mRNA in human CNS tissues. Neuropathol Appl Neurobiol 2001; 27:373-383.
	Sivakumar R, Barrett JA, Ironside JW, Playfer JR. Creutzfeldt-Jakob disease presenting as recurrent falls in an older person. Age Ageing 2001; 30(4): 356-357.
	Valleron A-J, Boelle P-Y, Will R, Cesbron J-Y. Estimation of epidemic size and incubation time based on age characteristics of vCJD in the United Kingdom. Science 2001; 294:1726-1728.
	Ward HJT. Epidemiology of variant CJD - an update. Cattle Practice BCVA 2001; 9(4):239-241.
	Will RG. Creutzfeldt-Jakob disease and BSE. In: Lock S, Last JM, Dunea G, editors. The Oxford Illustrated Companion to Medicine. Oxford: Oxford University Press, 2001: 206-207.
	Will RG. The facts about vCJD. The Practitioner 2001; 245:469-469.
	Wong B-S, Green AJE, Li R, Xie Z, Pan T, Liu T, Chen SG, Gambetti P, Sy M-S. Absence of protease resistant prion protein in the cerebrospinal fluid of Creutzfeldt-Jakob disease. J Pathology 2001; 194:9-14.
	Zeidler M, Collie DA, Macleod MA, Sellar RJ, Knight R. FLAIR MRI in sporadic Creutzfeldt-Jakob disease. Neurology 2001; 56:282.
2002	Alperovitch A, Will RG. Predicting the size of the vCJD epidemic in France. CR Biologies 2002;325:33-6. Armstrong RA, Cairns NJ, Ironside JW, Lantos P. Laminar distribution of the pathological changes in the cerebral cortex in variant Creutzfeldt-Jakob disease (vCJD). Folia Neuropathol 2002;40(4):165-71. Armstrong RA, Cairns NJ, Ironside JW, Lantos PL. Quantification of vacuolation ("spongiform change"), surviving neurone and prion protein deposition in eleven cases of variant Creutzfeldt-Jakob disease. Neuropathol Appl Neurobiol 2002;28(2):129-35. Armstrong RA, Cairns NJ, Ironside JW, Lantos PL. Quantitative variations in the pathology of 11 cases of variant Creutzfeldt-Jakob disease (vCJD). Pathophysiology 2002;8(4):235-41 . Armstrong RA, Cairns NJ, Ironside JW, Lantos PL. The spatial patterns of prion protein deposits in cases of variant Creutzfeldt-Jakob disease. Acta Neuropathol (Berl) 2002;104(6):665-9. Anonymous. Investigation of geographically associated cases of variant CJD in north east England. CDR Weekly 2002;12:3202. Barnett F. Nursing patients with variant Creutzfeldt-Jakob disease at home. British Journal of Community Nursing 2002;7(9):445-50. Bramble MG, Ironside JW. Creutzfeldt-Jakob disease: implications for gastroenterology. Gut 2002;50(6):888-90. Choe LH, Green A, Knight RSG, Thompson EJ, Lee KH. Apolipoprotein E and other cerebrospinal fluid proteins differentiate ante mortem variant Creutzfeldt-Jakob disease from ante mortem sporadic Creutzfeldt-Jakob disease. Electrophoresis 2002;23:2242-6. Connolly JG, Tate RJ, McLennan NF, Brown D, Telling GC, Fraser J, Head MW. Properties of the cellular prion protein expressed in Xenopus oocytes. Neuroreport 2002;13(9):1229-33. Esiri MM, Carter J, Ironside JW. Macrophage and microglial cell immunoreactivity for PrP(c) in a random post-mortem population. Neuropathol and Appl Neurobiol 2002;28(1):79-82. Forloni G, Iussich S, Awan T, Colombo L, Angeretti N, Girola L, Bertani I, Poli G, Caramelli M, Grazia Bruzzone M, Farina L, Limido L, Rossi G, Giaccone G, Ironside JW, Bugiani O, Salmona M, Tagliavini F. Tetracyclines affect prion infectivity. Proc Natl Acad Sci USA 2002;99(16):10849-54. Green AJE, Ramljak S, Muller WEG, Knight RSG, Schroder HC. 14-3-3 in the cerebrospinal fluid of patients with variant and sporadic Creutzfeldt-Jakob disease measured using capture assay able to detect low levels of 14-3-3 protein. Neurosci Lett 2002;324:57-60. Green AJE. Biochemical investigations in patients with dementia. Annals of Clinical Biochemistry 2002;39(3):211-20. Green AJE. Cerebrospinal fluid brain-derived proteins in the diagnosis of Alzheimer's disease and Creutzfeldt-Jakob disease. Neuropathol Appl Neurobiol 2002;28:427-40. Green AJE. Use of 14-3-3 in the diagnosis of Creutzfeldt-Jakob disease. Biochemical Society Transactions 2002;30 (4):382-6. Henry C, Knight R. Clinical features of variant Creutzfeldt-Jakob disease. Rev.Med.Virol. 2002;12:143-50. Henry C, Lowman A, Will RG. Creutzfeldt-Jakob disease in elderly people. Age and Ageing 2002;31:7-10. Hewitt P, Llewelyn C, and Will R. Follow up of donations from patients with vCJD. Vox Sanguinis 2002.;83: 1. Hilton DA, Ghani AC, Conyers L, Edwards P, McCardle L, Penney M, Ritchie D, Ironside JW. Accumulation of prion protein in tonsil and appendix: review of tissue samples. BMJ 2002;325:633. Ironside J, Lowman A. The diagnosis of variant Creutzfeldt-Jakob disease. Advances in Clinical Neuroscience & Rehabilitation 2002;1:6-8. Ironside JW, Head MW, McCardle L, Knight R. Neuropathology of variant Creutzfeldt-Jakob disease. Acta Neurobiol Exp 2002;62:175-82. Ironside JW, McCardle L, Horsburgh A, Lim Z, Head MW. Pathological diagnosis of variant Creutzfeldt-Jakob disease. APMIS 2002;110(1):79-87. Ironside JW. Neuropathology of variant Creutzfeldt-Jakob disease. C R Acad Sci III 2002;325(1):27-31. Kitamoto T, Mohri S, Ironside JW, Miyoshi I, Tanaka T, Kitamoto N, Itohara S, Kasai N, Katsuki M, Higuchi J, Muramoto T, Shin RW. Follicular dendritic cell of the knock-in mouse provides a new bioassay for human prions. Biochem Biophys Res Commun 2002;294(2):280-6. Knight R. CJD: are there distinct neuropsychological features? JNNP 2002;73:612-3. Knight R. CJD: the promise of treatment. The British Journal of Infection Control 2002;3:4. Knight R. Epidemiology of variant CJD. In: Brown F, Seitz R, eds. Advances in Transfusion Safety. Basel: Karger 2002: 87-92. Koperek O, Kovacs GG, Ritchie D, Ironside JW, Budka H, Wick G. Disease-associated prion protein in vessel walls. American Journal of Pathology 2002;161(6):1979-84. Kovacs GG, Head MW, Hegyi I, Bunn T, Flicker H, Hainfellner JA, McCardle L, Laszlo L, Jarius K, Ironside JW, Budka H. Immunohistochemistry for the prion protein: comparison of different monoclonal antibodies in human prion disease subtypes. Brain Pathology 2002;12(1):1-11. Kovacs GG, Trabattoni G, Hainfellner JA, Ironside JW, Knight RSG, Budka H. Mutations of the prion protein gene: phenotypic spectrum. J Neurol 2002;249:1567-82. Macleod MA, Stewart G, Zeidler M, Will RG, Knight R. Sensory features of variant Creutzfeldt-Jakob disease. J Neurol 2002;249:706-11. McCormack JE, Baybutt HN, Everington D, Will RG, Ironside JW, Manson JC. PRNP contains both intronic and upstream regulatory regions that may influence susceptibility to Creutzfeldt-Jakob disease. Gene 2002;288:139-46. Minghetti L, Cardone F, Greco A, Puopolo M, Levi G, Green AJE, Knight R, Pocchiari M. Increased CSF levels of prostaglandin E2 in variant Creutzfeldt-Jakob disease. Neurology 2002;58:127-9. Molesworth A, Cousens S, Ward H (reporters). Rising incidence of Creutzfeldt-Jakob disease in Switzerland. Eurosurveillance Weekly 2002;29:020728. Molesworth A, Horby P, Ward H (reporters). Variant Creutzfeldt-Jakob disease in a Canadian resident. Eurosurveillance Weekly 2002;33:020815. Molesworth A, Pritchard L, Ward H (reporters). Low incidence of Creutzfeldt-Jakob disease in Europe. Eurosurveillance Weekly 2002;44;021031. Myles S, Douglas MJ, Ward HJT, Campbell H, Will RG. Variant Creutzfeldt-Jakob disease: costs borne by families. Health and Social Care in the Community 2002;10(2):91-8. Sasaki K, Doh-ura K, Ironside JW, Iwaki T. Increased clusterin (apolipoprotein J) expression in human and mouse brains infected with transmissible spongiform encephalopathies. Acta Neuropathol (Berl) 2002;103(3):199-208. Sellars RJ, Collie DA, Will RG. Progress in understanding Creutzfeldt-Jakob disease. Am J Neuroradiol 2002;23:1070-2. Spencer MD, Knight RSG, Will RG. First hundred cases of variant Creutzfeldt-Jakob disease: retrospective case note review of early psychiatric and neurological features. BMJ 2002;324:1479-82. Summers DM, Collie DA, Sellar RJ, Zeidler M, Knight R, Will RG, Ironside JW. 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