Human stem cell derived neurones and astrocytes as an in vitro model of human prion infection and replication

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Human stem cell derived neurones and astrocytes as an in vitro model of human prion infection and replication

Principal Investigator:  Dr MW Head

This NC3Rs funded study, initiated in 2015 is a collaboration with Professor Siddharthan Chandran within the University of Edinburgh Centre for Clinical Brain Sciences.  The study seeks to explore the potential for astrocytes and neurones derived from induced pluripotent human stem cells to replace animal models in aspects of human prion disease research.

https://www.nc3rs.org.uk/human-stem-cell-derived-neurones-and-astrocytes...